This resource provides a deep dive into each of the Teen Pregnancy Prevention (TPP) Tier 2 Adolescent Sexual Health Innovation Hubs grant expectations. The purpose is to provide a clear blueprint to recipients to support them in achieving the goal of the funding opportunity which is to identify and support multiple cohorts of innovation development teams to develop, refine, and test additional models and innovative strategies intended to reduce unintended teen pregnancy, sexually transmitted infections (STIs), or associated risk factors, and promote positive youth development.